Step 1: Understanding the Concept:
Antibodies, or immunoglobulins (Ig), are Y-shaped proteins produced by plasma cells to neutralize pathogens.
Step 2: Detailed Explanation:
There are five main classes of antibodies in humans, abbreviated as GAMED:
1. IgG: The most abundant antibody in the blood; it can cross the placenta.
2. IgM: Usually the first antibody produced during a primary immune response.
3. IgA: Found in secretions like saliva, tears, and colostrum (first milk).
4. IgE: Involved in allergic reactions and defense against parasites.
5. IgD: Primarily acts as an antigen receptor on B-cell surfaces.
Any two of these can be mentioned as participants in the humoral response.
Step 3: Final Answer:
Two types of antibodies are IgG and IgM.