Step 1: Understanding mutation.
Mutation refers to a sudden and permanent change in the DNA sequence of an organism. It can affect genes or chromosomes and may lead to variations.
Step 2: Nature of mutations.
Mutations occur abruptly and are heritable if they take place in germ cells. They are not gradual changes and are different from continuous variations seen in populations.
Step 3: Analysis of options.
(A) Irreversible, gradual change: Incorrect, mutations are sudden, not gradual.
(B) Sudden change in genetic material: Correct definition of mutation.
(C) Non-inheritable gradual change: Incorrect, many mutations are inheritable.
(D) Small and continuous variations: Describes variations, not mutations.
Step 4: Conclusion.
Mutation is correctly defined as a sudden change in genetic material.