Question

Match the components of List I with those of List II:

• A. A-IV, B-II, C-III, D-I
• B. A-I, B-II, C-III, D-IV
• C. A-II, B-III, C-IV, D-I
• D. A-IV, B-I, C-II, D-III

Hint:

Hill = Hemoglobin; Milstein = Monoclonal; Kendrew = Myoglobin.

Answer 1

The Correct Option is D

Step 1: Concept
This question requires matching major biochemical and biological discoveries with the scientists responsible for them.

Step 2: Analysis
A-IV: Archibald Hill described the cooperative binding of oxygen to hemoglobin (Hill equation). B-I: Cesar Milstein (with Georges Köhler) developed the technique for monoclonal antibody production. C-II: John Kendrew solved the first 3D structure of a protein (myoglobin) using X-ray diffraction. D-III: Victor Henri proposed the intermediate enzyme-substrate complex as a prerequisite for catalysis.

Step 3: Conclusion
The correct mapping follows the pattern A-IV, B-I, C-II, D-III. Final Answer: (D)