Question

Match List-I with List-II

List-I (Disease Condition)	List-II (Pathogen involved)
(A) Bacillary dysentry	(I) Brucella abortus
(B) Hemolytic uremic syndrome	(II) Coxiella burnetii
(C) Malta fever	(III) Shigella spp.
(D) Q fever	(IV) Escherichia coli O157:H7

Choose the correct answer from the options given below

• (A) - (I), (B) - (II), (C) - (III), (D) - (IV)
• (A) - (I), (B) - (III), (C) - (II), (D) - (IV)
• (A) - (I), (B) - (II), (C) - (IV), (D) - (III)
• (A) - (III), (B) - (IV), (C) - (I), (D) - (II)

Hint:

To remember key dairy zoonoses:
- Q Fever \(\rightarrow\) Coxiella burnetii (defines pasteurization limits).
- Malta/Undulant Fever \(\rightarrow\) Brucella spp.
- HUS \(\rightarrow\) STEC (E. coli O157:H7).
- Dysentery \(\rightarrow\) Shigella spp.

Answer 1

The Correct Option is D

Step 1: Understanding the Concept:
Raw milk and dairy products can act as vehicles for transmitting zoonotic and foodborne pathogens to humans.
Each pathogen is associated with specific clinical manifestations and diseases.

Step 2: Detailed Explanation:
Let us match each disease condition in List-I with its causative pathogen in List-II:
-(A) Bacillary dysentery:
This is an acute bacterial infection of the intestine characterized by severe abdominal cramps and stools containing blood and mucus.
It is primarily caused by species of the genus Shigella (such as S. dysenteriae, S. flexneri, and S. sonnei).
Therefore, (A) matches with (III).
-(B) Hemolytic uremic syndrome (HUS):
HUS is a severe, life-threatening complication characterized by acute renal failure, hemolytic anemia, and a low platelet count.
It is caused by Shiga toxin-producing Escherichia coli (STEC) strains, with E. coli O157:H7 being the most common serotype.
Therefore, (B) matches with (IV).
-(C) Malta fever:
Also known as Brucellosis, undulant fever, or Mediterranean fever, this zoonotic infection is transmitted to humans through raw milk from infected animals.
It is caused by Brucella species, including Brucella abortus (from cattle) and Brucella melitensis (from sheep and goats).
Therefore, (C) matches with (I).
-(D) Q fever:
Q fever is a widespread zoonotic disease caused by Coxiella burnetii, an obligate intracellular bacterium.
It is highly resistant to environmental stressors and heat, and its survival during thermal processing is used as the standard to define pasteurization parameters.
Therefore, (D) matches with (II).
This matching sequence corresponds to Option (D).

Step 3: Final Answer:
The correct matching sequence is (A) - (III), (B) - (IV), (C) - (I), (D) - (II).