Question

Match List-I with List-II:

Choose the correct answer from the options given below:

• (A) - (II), (B) - (III), (C) - (I), (D) - (IV)
• (A) - (IV), (B) - (III), (C) - (I), (D) - (II)
• (A) - (III), (B) - (IV), (C) - (I), (D) - (II)
• (A) - (IV), (B) - (II), (C) - (III), (D) - (I)

Hint:

Concanavalin A (ConA) is the classic plant lectin studied in biochemistry.
Cholera toxin (CT) is produced by the bacterium Vibrio cholerae.
Linking these two quickly isolates the correct option (B).

Answer 1

The Correct Option is B

Step 1: Understanding the Concept:
Lectins are highly specific carbohydrate-binding proteins found across all domains of life.
They facilitate cell-to-cell contact, pathogen binding, and immune recognition.

Step 2: Detailed Explanation:
- Concanavalin A, ConA (A): A well-known lectin originally extracted from the Jack bean (Canavalia ensiformis), making its source Plant (IV).
- Mannose-Binding Protein/Lectin, MbpA (B): A calcium-dependent lectin synthesized by hepatocytes in animals that plays a role in innate immunity, making its source Animal (III).
- Cholera Toxin, CT (C): An oligomeric enterotoxin produced by the bacterium Vibrio cholerae that binds to cell surface glycolipids, making its source Bacteria (I).
- Viral Protein 1, VP1 (D): A structural capsid protein in several non-enveloped viruses (such as polyomaviruses) that acts as a lectin during cell attachment, making its source Viral (II).

Step 3: Final Answer:
The correct matching sequence is (A) - (IV), (B) - (III), (C) - (I), (D) - (II), corresponding to option (B).