Question

Match List-I with List-II:

Choose the correct answer from the options given below:

• (A) - (I), (B) - (II), (C) - (III), (D) - (IV)
• (A) - (I), (B) - (III), (C) - (II), (D) - (IV)
• (A) - (I), (B) - (II), (C) - (IV), (D) - (III)
• (A) - (III), (B) - (IV), (C) - (I), (D) - (II)

Hint:

A simple memory hook for collagen locations:
- Type I: "Bone" (and general connective tissues).
- Type II: "Cartilage".
- Type IV: "Under the floor" (Basement membrane).

Answer 1

The Correct Option is A

Step 1: Understanding the Concept:
Collagen is the most abundant structural protein in mammals, forming a major component of connective tissues.
More than 28 types of collagen exist, designated by Roman numerals, each localized to specific anatomical sites.

Step 2: Detailed Explanation:
- Type I Collagen (A): The most abundant collagen type, forming thick fibers found in bone, skin, tendons, and most connective tissues (I).
- Type II Collagen (B): Found in loose, thin fibrils primarily in cartilage (II) and the vitreous humor of the eye.
- Type III Collagen (C): Often found alongside Type I in elastic structures like skin, blood vessels, and lungs (III).
- Type IV Collagen (D): Forms a sheet-like network (rather than fibrils) that constitutes the structural framework of the basement membrane (IV).

Step 3: Final Answer:
The correct matching sequence is (A) - (I), (B) - (II), (C) - (III), (D) - (IV), corresponding to option (A).