Concept:
Several pioneering microbiologists made landmark contributions that laid the foundation of microbiology, immunology, and medical science.
Step 1: Matching Robert Koch.
Robert Koch developed:
\[
\text{Pure culture technique}
\]
and established Koch’s postulates for disease causation.
Thus:
\[
A \rightarrow IV
\]
Step 2: Matching Paul Ehrlich.
Paul Ehrlich introduced the:
\[
\text{Concept of chemotherapy}
\]
and developed the idea of “magic bullets”.
Thus:
\[
B \rightarrow I
\]
Step 3: Matching Sergei N. Winogradsky.
Winogradsky discovered important soil microorganisms including:
\[
\text{Nitrogen-fixing bacteria}
\]
and contributed greatly to soil microbiology.
Thus:
\[
C \rightarrow II
\]
Step 4: Matching Jules Bordet.
Jules Bordet is known for work on:
\[
\text{Complement fixation reaction}
\]
which became important in immunology and serological testing.
Thus:
\[
D \rightarrow III
\]
Step 5: Determining the correct combination.
Therefore:
\[
\boxed{
A\text{-IV},\
B\text{-I},\
C\text{-II},\
D\text{-III}
}
\]
Hence, the correct answer is:
\[
\boxed{(B)\ A\text{-IV},\ B\text{-I},\ C\text{-II},\ D\text{-III}}
\]