Question

What is the net yield of ATP molecules produced during the glycolysis of one glucose molecule?

• A. 2 ATP
• B. 4 ATP
• C. 6 ATP
• D. 8 ATP

Hint:

Glycolysis → Invest 2 ATP, produce 4 ATP → Net gain = 2 ATP.

Answer 1

The Correct Option is A

Concept: Glycolysis is the first stage of cellular respiration, occurring in the cytoplasm, where one molecule of glucose is broken down into two molecules of pyruvate.
Step 1: ATP investment phase.
During the initial steps of glycolysis, 2 ATP molecules are consumed.
Step 2: ATP generation phase.
In later steps, 4 ATP molecules are produced through substrate-level phosphorylation.
Step 3: Net ATP calculation.
\[ \text{Net ATP} = 4 - 2 = 2 \]
Step 4: Additional products.

• 2 NADH molecules
• 2 pyruvate molecules

Step 5: Conclusion.
Thus, the net gain of ATP from glycolysis of one glucose molecule is 2 ATP.