Question:
Kupffer cells are an active form of
Kupffer cells are an active form of
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Be familiar with the organ-specific names of monocytes/macrophages:
- Liver = Kupffer cells
- Brain = Microglia
- Lungs = Alveolar macrophages
- Bone = Osteoclasts
- Connective Tissue = Histiocytes
- Liver = Kupffer cells
- Brain = Microglia
- Lungs = Alveolar macrophages
- Bone = Osteoclasts
- Connective Tissue = Histiocytes
Updated On: Jul 8, 2026
- Besophil
- Neutrophil
- Monocyte
- Lymphocyte
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The Correct Option is C
Solution and Explanation
Step 1: Understanding the Concept:
The Mononuclear Phagocyte System (MPS) consists of closely related phagocytic cells located throughout different body tissues, all sharing a common bone marrow origin.
Step 3: Detailed Explanation:
- Monocytes are produced in the bone marrow, enter the circulation, and migrate into various organs.
- Once in tissues, monocytes differentiate into specialized, tissue-specific macrophages.
- Kupffer cells are specialized macrophages that reside in the sinusoids of the liver, phagocytosing damaged erythrocytes, cellular debris, and circulating pathogens.
Therefore, Kupffer cells represent a tissue-resident active form of monocytes.
Step 4: Final Answer
Kupffer cells are differentiated tissue forms of blood monocytes.
The Mononuclear Phagocyte System (MPS) consists of closely related phagocytic cells located throughout different body tissues, all sharing a common bone marrow origin.
Step 3: Detailed Explanation:
- Monocytes are produced in the bone marrow, enter the circulation, and migrate into various organs.
- Once in tissues, monocytes differentiate into specialized, tissue-specific macrophages.
- Kupffer cells are specialized macrophages that reside in the sinusoids of the liver, phagocytosing damaged erythrocytes, cellular debris, and circulating pathogens.
Therefore, Kupffer cells represent a tissue-resident active form of monocytes.
Step 4: Final Answer
Kupffer cells are differentiated tissue forms of blood monocytes.
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