Question

In which of the following human diseases does the body's self-defence mechanism attack self-cells?

• A. Thalassemia
• B. Phenylketonuria
• C. Filariasis
• D. Rheumatoid arthritis

Hint:

Autoimmune diseases like rheumatoid arthritis occur when the immune system fails to distinguish self from non-self and begins to attack the body's own cells.

Answer 1

The Correct Option is D

Rheumatoid arthritis is an autoimmune disorder in which the body’s immune system mistakenly attacks its own tissues, especially the synovial joints. This results in inflammation, pain, and damage to joint linings. Unlike infections caused by external pathogens, autoimmune diseases arise from a failure of self-tolerance in the immune system.