Question:
Formation of peptide bond between amino acids during translation is catalyzed by __________.
Formation of peptide bond between amino acids during translation is catalyzed by __________.
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Peptide bond formation is catalysed by an RNA molecule acting as an enzyme in the ribosome.
Updated On: Nov 12, 2026
- Ribozyme
- Polynucleotide phosphorylase
- Permease
- Transacetylase
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The Correct Option is A
Solution and Explanation
Step 1: Understanding the Concept
During translation, amino acids are joined by peptide bonds on the large subunit of the ribosome.
Step 2: The catalyst
The reaction is carried out by peptidyl transferase activity, which resides in the rRNA (23S rRNA in bacteria). An RNA that acts as an enzyme is called a ribozyme.
Step 3: Other options
Polynucleotide phosphorylase makes RNA without a template. Permease and transacetylase are products of the lac operon.
Final Answer:
Peptide bond formation is catalysed by a ribozyme. \[ \boxed{\text{(A) }\text{Ribozyme}} \]
During translation, amino acids are joined by peptide bonds on the large subunit of the ribosome.
Step 2: The catalyst
The reaction is carried out by peptidyl transferase activity, which resides in the rRNA (23S rRNA in bacteria). An RNA that acts as an enzyme is called a ribozyme.
Step 3: Other options
Polynucleotide phosphorylase makes RNA without a template. Permease and transacetylase are products of the lac operon.
Final Answer:
Peptide bond formation is catalysed by a ribozyme. \[ \boxed{\text{(A) }\text{Ribozyme}} \]
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