Question

All the 64 codons in the dictionary of genetic code were deciphered by \rule{2cm{0.15mm}}

• A. Watson and Crick
• B. Dr. Har Gobind Khorana
• C. Yanofski and Sarabhai
• D. Nirenberg, Matthaei and Ochoa

Hint:

Memory line: Nirenberg $\rightarrow$ First codon
Khorana $\rightarrow$ All codons

Answer 1

The Correct Option is B

Concept: Deciphering the genetic code was a major milestone in molecular biology.
• Nirenberg and Matthaei discovered the first codon (UUU for phenylalanine).
• Further work was done to identify other codons.
• Dr. Har Gobind Khorana synthesized RNA sequences and helped identify all 64 codons.

Step 1: Understand contributions.
• Watson and Crick: DNA structure
• Nirenberg and Matthaei: First codon deciphered
• Khorana: Complete decoding of all codons

Step 2: Identify correct scientist.
Khorana played the key role in deciphering the entire genetic code.

Step 3: Conclusion.
Thus, all 64 codons were deciphered by Dr. Har Gobind Khorana. Final Answer: Option (B)