Question:

Failure of segregation of chromatids during cell division results in gain or loss of chromosomes. Select the correct option.

Show Hint

Nondisjunction gives gain or loss of single chromosomes, which is aneuploidy.
Updated On: Oct 23, 2026
  • Euploidy
  • Monoploidy
  • Aneuploidy
  • Polyploidy
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The Correct Option is C

Solution and Explanation

Step 1: Understand the question:
When chromatids fail to separate during anaphase, this is called nondisjunction.
One daughter cell then gets an extra chromosome and the other loses one.

Step 2: Name the condition:
Gain or loss of one or a few chromosomes, without a change in whole sets, is called aneuploidy.
Down syndrome (trisomy 21) and Turner syndrome (XO) are examples.

Step 3: Check the other options:
Euploidy means a change in complete chromosome sets, so it is not about single chromosomes. So (A) is wrong.
Monoploidy means only one set of chromosomes. So (B) is wrong.
Polyploidy means more than two complete sets, which results from failure of cytokinesis after chromosome replication. So (D) is wrong.

Final Answer:
The correct option is (C) Aneuploidy.
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