Question:

Example for polyene antifungal antibiotic.

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Polyene = Many double bonds. Amphotericin B and Nystatin are the main ones.
  • Clotrimazole
  • Ketoconazole
  • Amphotericin
  • Griseofulvin
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The Correct Option is C

Solution and Explanation

Step 1: Concept
Antifungal agents are classified based on their chemical structure and mechanism of action.

Step 2: Meaning

Polyene antibiotics contain a large macrocyclic ring with multiple conjugated double bonds.

Step 3: Analysis

Clotrimazole and Ketoconazole are azoles. Griseofulvin is a benzofuran derivative. Amphotericin B (and Nystatin) are the classic examples of polyene antibiotics.

Step 4: Conclusion

Consequently, Amphotericin is the correct example of a polyene antifungal agent.

Final Answer: (C)
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