Assertion (A) : The human blood group "AB" exemplifies co-dominance.
Reason (R) : The gene for human blood group trait exists in three allelic forms \( \mathrm{I^{A}} \), \( \mathrm{I^{B}} \) and i.
A child with blood group A has father with blood group B and the mother with blood group AB. Choose the option that gives the correct genotypes of father, mother, and the child:

The diagram below shows the sequence of amino acids in part of haemoglobin molecule.
[Diagram: haemoglobin chain Val, His, Leu, Thr, Pro, Glu, Glu; mRNA line; DNA line with triplets CAT, GTA, AAT, TGA, GGA, CTT (the T marked with *), CTC. Key: Val = valine, His = histidine, Leu = leucine, Thr = threonine, Pro = proline, Glu = glutamic acid]
(i) If the base T (marked with *) is substituted with A, in "CTT" of DNA strand how would it affect the haemoglobin chain ?
(ii) Name the condition and the effects associated with the above substitution.

(i) Differentiate between Mendelian and Chromosomal disorders.
(ii) Which disorder is known as "Inborn Error of Metabolism" ? Mention its cause and any one symptom. Name the harmful compounds formed.
A woman having genes for haemophilia on one X chromosome and a gene for colour blindness on another X chromosome marries a normal man. The progeny will show