A wheel of mass \( 4M \) and radius \( R \) is made of a thin uniform distribution of mass \( 3M \) at the rim and a point mass \( M \) at the center. The spokes of the wheel are massless. The center of mass of the wheel is connected to a horizontal massless rod of length \( 2R \), with one end fixed at \( O \), as shown in the figure. The wheel rolls without slipping on horizontal ground with angular speed \( \Omega \). If \( \vec{L} \) is the total angular momentum of the wheel about \( O \), then the magnitude \( \left| \frac{d\vec{L}}{dt} \right| = N(MR^2 \Omega^2) \). The value of \( N \) (in integer) is:
A wheel of mass \( 4M \) and radius \( R \) is made of a thin uniform distribution of mass \( 3M \) at the rim and a point mass \( M \) at the center. The spokes of the wheel are massless. The center of mass of the wheel is connected to a horizontal massless rod of length \( 2R \), with one end fixed at \( O \), as shown in the figure. The wheel rolls without slipping on horizontal ground with angular speed \( \Omega \). If \( \vec{L} \) is the total angular momentum of the wheel about \( O \), then the magnitude \( \left| \frac{d\vec{L}}{dt} \right| = N(MR^2 \Omega^2) \). The value of \( N \) (in integer) is:

Given below are two statements:
Statement I: Transfer RNAs and ribosomal RNA do not interact with mRNA.
Statement II: RNA interference (RNAi) takes place in all eukaryotic organisms as a method of cellular defence.
In the light of the above statements, choose the most appropriate answer from the options given below: