List of top Medical Questions asked in NEET SS

A patient diagnosed with dengue initially improved but later returned with high-grade fever, severe thrombocytopenia (platelet count 15,000), and leukopenia. What is the next best investigation to evaluate the cause?
A 58-year-old patient in the ICU develops fever, cough, and breathlessness 5 days after being on mechanical ventilation. Chest X-ray shows bilateral infiltrates. MRSA is isolated from the tracheal aspirate culture with a vancomycin MIC of 1.5 $\mu$g/mL, and the platelet count is 40,000/cmm. What is the most appropriate antibiotic choice for this patient?
A 35-year-old man presents with high-grade fever, right upper quadrant abdominal pain, and tender hepatomegaly. He has no history of jaundice. An abdominal CT scan shows a solitary hypoechoic lesion in the right lobe of the liver, suggestive of a liver abscess. What is the most appropriate next step in management?
An 27 year old patient presents with peripheral neuropathy normal immunoglobulin levels and recurrent cutaneous infections. autoimmune thyroiditis and low C3 was also seen which of the following is the most likely diagnosis?
A patient presents with the fever Arthritis and a Salmon coloured rash on the trunk laboratory findings show decreased CD 25 expression. What is the most likely diagnosis?
Cancer associated cachexia is primarily mediated by which of the following cytokines?
In anaphylaxis, bronchoconstriction is primarily mediated by which of the following inflammatory mediators?
Neer’s impingement test is used to diagnose which of the following conditions?
A woman presents with widespread pain, multiple tender joints, fatigue and sleep disturbances with no signs of joint swelling or systemic inflammation. What is the next step in evaluation?
A patient presents with widespread pain and multiple comorbidities. Which of the following clinical scenarios is most consistent with fibromyalgia?
A patient presents with acute-onset monoarthritis with severe joint pain, erythema, and swelling suggestive of gout. What is the gold standard investigation for diagnosis?
A patient with IgG4-related disease with pancreatitis initially responded to steroid therapy but experienced a relapse (gland size increased) after tapering. What is the next step in treatment?
A 32 year old male present with chronic low back pain for the past 6 months. the pain is insidious in onset version in morning and improve with moment he also reports alternating buttocks pain. What is the most likely diagnosis?
What is the preferred initial treatment for acute gouty arthritis?
A patient presents with recurrent skin eruptions and bone pain. Laboratory tests show elevated ESR and CRP. Imaging demonstrates the “bull’s head” sign on the sternoclavicular region. Which of the following is the most appropriate initial treatment for this condition?
A 50 year old male with rheumatoid arthritis (RA) for 10 years on treatment presents with a non healing ulcer on the lower limb and stocking-glove neuropathy. What is the most likely cause?
Which of the following is a poor prognostic factor in rheumatoid arthritis?
A female patient with rheumatoid arthritis(RA) is currently on methotrexate (MTX), sulfasalazine (SSZ), and hydroxychloroquine (HCQ) and is planning for pregnancy. What is the appropriate next step in medication management?
A patient presents with arthritis involving both DIP and PIP joints, with erosions and new bone formation. There are no skin manifestations. What is the most likely diagnosis?
A 28 year old male presents with asymmetric oligoarthritis involving the knees and ankles, along with a history of dysuria and diarrhea 3 weeks ago. On examination, he has conjunctival infection, painless shallow oral ulcers also. Which of the following findings is most commonly associated with this condition?
The image shows a hand deformity. What is the most likely diagnosis?
42-year-old female, with diffuse cutaneous systemic sclerosis, presents with SOB/cough. CXR shows ILD. FVC 50% predicted, DLCO 30% predicted. ECG and imaging shows right ventricular enlargement and dilated PA s/o pulmonary hypertension. Most appropriate next step in management is?
A young male presents with rapidly worsening kidney function. Urinalysis shows hematuria, 3+ proteinuria, and red blood cell casts. His serum creatinine is 3.2 mg/dL. Chest imaging reveals bilateral pulmonary nodules. Which of the following is the most appropriate initial management?
A female presents with malar rash and her serology is positive for ANA and dsDNA antibodies. What is the most likely diagnosis?
60-year old male with RA on MTX for 5 years presents with SOB and cough. Chest examination reveals end-inspiratory crackles. HRCT shows reticular opacities and traction bronchiectasis (UIP pattern). Which of the following is correct?