List of top Medical Questions asked in NEET SS

A 25-year-old man presents to the emergency department with dry mouth, dilated pupils, flushed skin, urinary retention, tachycardia, and altered sensorium after consuming seeds from a wild plant while trekking. His friends report that the plant was identified as Atropa belladonna. Which of the following is the specific antidote for this poisoning?

Which of the following is a key current limitation in the use of Artificial Intelligence (AI) for cancer diagnosis and management?

A 45-year-old man is brought to the emergency department with confusion and rapid breathing after being found unconscious at home. Arterial blood gas analysis shows pH 7.10 and an anion gap of 18. Toxicology screening is pending. Which of the following substances is least likely to be responsible for his condition?

An unconscious patient presents with bilateral pinpoint pupils and partial improvement after administration of both naloxone and flumazenil. Which combination of substances has most likely been consumed?

A 35-year-old man with known autosomal dominant polycystic kidney disease (ADPKD) presents with sudden-onset right flank pain and mild hematuria. He denies fever, dysuria, or recent trauma. Ultrasound shows enlarged cystic kidneys with no evidence of renal mass. Which of the following is least likely to be the cause of flank pain in this condition?

An elderly man with end-stage metastatic lung carcinoma on palliative care is receiving morphine for severe pain. Despite escalating doses, he continues to experience significant pain relief with mild drowsiness but develops a respiratory rate of 8/min and oxygen saturation of 88%. What factor should now determine the maximum permissible dose of morphine in this patient?

A 55-year-old woman receiving chemotherapy for breast cancer develops burning pain and tingling in both feet. Which of the following is considered the first-line pharmacologic treatment for cancer-related neuropathic pain?

A 65-year-old man presents with a 1-year history of slowness of movement and mild resting tremor in his right hand. Over the past few months, he has also developed rigidity on the same side, but the left side remains normal. There is no history of antipsychotic use or cerebrovascular disease. Which of the following features most strongly supports the diagnosis of idiopathic Parkinson’s disease?

A 30-year-old woman presents with a unilateral throbbing headache associated with photophobia, phonophobia, and osmophobia. Each episode lasts for 4-6 hours and improves with rest. What is the most likely diagnosis?

A 68-year-old man with hypertension and coronary artery disease undergoes percutaneous coronary intervention (PCI) for unstable angina. Two weeks later, he presents with fatigue, worsening renal function (creatinine 3.1 mg/dL from baseline 1.2 mg/dL), eosinophilia, and a serpiginous, mottled rash over both legs. Which of the following is the most likely diagnosis?

A 45-year-old man is found to have microscopic hematuria on urinalysis. Phase-contrast microscopy shows acanthocytes and RBC casts. Which of the following best describes the underlying pathology?

A 60-year-old man with long-standing hypertension and deteriorating renal function undergoes evaluation for secondary causes of hypertension. Which of the following statements regarding the diagnosis of renal artery stenosis (RAS) is most accurate?

A 62-year-old male with unresectable cholangiocarcinoma is planned for systemic therapy. Which regimen forms the current standard first-line chemotherapy for advanced disease?

A 30-year-old hypertensive male presents with grade II hypertensive retinopathy. Which investigation is most useful to guide further management and detect target organ damage?

A 40-year-old woman presents with left flank pain. Non-contrast CT KUB shows a 3-4 mm distal ureteric stone. She is afebrile, hemodynamically stable, and shows no signs of obstruction or infection. What is the most appropriate initial management?

In a patient with Burkitt lymphoma undergoing chemotherapy, grading of tumor lysis syndrome is based on which classification system that defines both laboratory and clinical TLS?

A 68-year-old male develops worsening renal function one week after undergoing CABG. He also has livedo reticularis and eosinophilia. Which urinary finding best supports the diagnosis of cholesterol crystal embolism?

A patient presents with facial plethora, dilated chest wall veins, and dyspnea due to superior vena cava obstruction (SVCO). Which of the following malignancies is least likely to cause SVCO?

Peripheral smear shows sickle-shaped RBCs in a known case of sickle cell disease. Which of the following is the best drug for disease modification?

High-performance liquid chromatography (HPLC) shows HbS very high with HbA around 40%. What is the most likely diagnosis?

A patient presents with thrombocytopenia, elevated bilirubin, rising creatinine, and elevated LDH. ADAMTS13 activity is 45%. What is the most appropriate next step in management?

A 45-year-old male presents with recurrent episodes of flushing, abdominal discomfort, and splenomegaly. Laboratory studies show elevated serum tryptase levels. Bone marrow biopsy reveals mast cells positive for CD117 and CD25. According to the WHO criteria, which of the following findings fulfills the major diagnostic criterion for systemic mastocytosis?

Which of the following disorders is most commonly linked with ischemic stroke caused by a hypercoagulable (prothrombotic) state?

A patient with acute graft-versus-host disease (GVHD) following allogeneic stem cell transplantation shows no clinical improvement despite treatment with high-dose corticosteroids. Which of the following is the next best drug to use?

TH2 inflammation is mediated by which of the following cytokines?