List of top Questions asked in GPAT

Given below are two statements
Statement I: Drugs Controller General of India is the Chairman of Drugs Technical Advisory Board (DTAB) 
Statement II: In DTAB, there will be eight ex‐officio members, five nominated and five elected members 
In light of the above statements, choose the most appropriate answer from the options given below

Citric acid cycle is the final pathway during the oxidation of _______ .

Which of the following is an example of a thermosetting plastic material?

Regarding Bromocriptine, which of the following statement is TRUE‐ It is a relatively selective dopamine D2 agonist with prominent action
A. on pituitary lactotrophs (inhibit prolactin release) 
B. in striatum (antiparkinsonian) 
C. in CTZ (antiemetic) ATP γ K 5) 6) 7) 
D. as an adjunctive treatment for type 2 DM 
Choose the correct answer from the options given below:

Cottrell’s method is used for the measurement of:

Boric acid with molecular weight 61.83 was partitioned between water and amyl alcohol at 25 °C. The amount of boric acid was determined to be 0.24 g in 250 ml of amyl alcohol and 0.32 g in 100 ml water. The partition coefficient of boric acid between water and amyl alcohol, when calculated at molar concentration for each of the solution, is:

___ is the practice of pharmacy in private and government‐owned hospitals, health maintenance organizations (HMOs), clinics, walk‐in health centers, and nursing homes.

Which of the following DRYERS is a "static bed dryer"?

A neonate suffering from icterus is intravenously administered with phenobarbital. The justification for this therapy is:

Match List I with List II

	List I-Mechanism of action		List II-Drugs
A	DPP4 inhibitors	I	Metformin
B	KATP Channel blocker	II	Pioglitazone
C	PPAR activator	III	Glimepiride
D	AMP Activator	IV	Teneligliptin
E	-	V	α glucosidase inhibitors

Choose the correct answer from the options given below:

Statement I: The problem of declining potency in an unstable preparation can be ameliorated by the addition of an excess or overage of the active ingredient.
Statement II: Overages, are added to pharmaceutical formulations to keep the content of the active ingredient well above the limit, compatible with therapeutic requirements, for a predetermined period of time

India’s first Central Drug Laboratory was established at

Match the statements in List I with their correct answers in List II, respectively, in respect to modified 1st law of thermodynamics, and

List I		List II
A	Constant heat (q = 0)	I	Isothermal
B	Reversible process at constant temperature (dT = 0)	II	Isometric
C	Constant volume (dV = 0)	III	Adiabatic
D	Constant pressure (dP = 0)	IV	Isobar

Choose the correct answer from the options given below:

The ‘Up‐and‐Down’ method for a projected LD50 determination is described in the…..

Given below are two statements, one is labelled as Assertion A and the other is labelled as Reason R
Assertion A: In the manufacturing of glycero‐gelatin suppositories, overfilling of mould is necessary. 
Reason R: Glycero‐gelatin bases contract very little on cooling and the excess cannot be neatly removed. 
In light of the above statements, choose the correct answer from the options given below

In the process of extraction, if maceration is accomplished by heating the drug and solvent in a close vessel, then this modification is known as _____

Which one of the following is NOT a phospholipid?

HPTLC analysis is useful for following types of analysis of herbal drugs
A. Quantitative estimation of marker compound 
B. Authentication of extracts 
C. Detection of pesticides 
D. Standardization of herbal drugs 
Choose the correct answer from the options given below:

Optically active mandelic acid can be synthesized from benzaldehyde in the presence of the enzyme:

Tropane nucleus is combination of

Match List I with List II

	List I-(Poisoning)		List II-(Treatment)
A	Warfarin	I	Pralidoxime
B	Carbon monoxide	II	Oxygen
C	Cyanide	III	Vitamin K
D	Nitrites	IV	Dicobalt edatate
E	Organophosphates	V	Methylene blue

Choose the correct answer from the options given below:

Given below are the two statements
Statement I: Glucose‐6‐phosphate can be formed from glucose, but not from glycogen.
Statement II: Glucose‐1‐phosphate may be hydrolyzed to yield free glucose in liver.
Choose the most appropriate answer from the options given below:

Given below are two statements, one is labelled as Assertion A and the other is labelled as Reason R
Assertion A: During the process of decompression in tablet manufacturing, expansion occurs in some tablet. 
Reason R: Expansion occurs in some tablet because of Plastic deformation that has occurred during compression process. 
In light of the above statements, choose the correct answer from the options given below