Step 1: Understanding the Concept
Second messengers carry the hormone signal inside the cell.
Step 2: List
Common ones are cAMP, cGMP, \(\text{IP}_3\), DAG and \(\text{Ca}^{++}\).
Step 3: Conclusion
\(\text{Mg}^{++}\) is not a second messenger.
Final Answer:
Magnesium ion is not a second messenger.
\[ \boxed{\text{(D) }\text{Mg}^{++}} \]