Question:
Which one of the following is an alkylating agent?
Which one of the following is an alkylating agent?
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Common alkylating agents include Cyclophosphamide and Chlorambucil.
Updated On: May 19, 2026
- Methotrexate
- Chlorambucil
- Dactinomycin
- Vincristine
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The Correct Option is B
Solution and Explanation
Step 1: Concept
Alkylating agents are a class of chemotherapy drugs that work by adding an alkyl group to DNA.
Step 2: Meaning
This chemical modification causes DNA cross-linking, which prevents the cell from replicating and eventually leads to cell death.
Step 3: Analysis
Methotrexate is an antimetabolite. Vincristine is a vinca alkaloid (microtubule inhibitor). Dactinomycin is an antitumor antibiotic. Chlorambucil is a nitrogen mustard derivative and a classic alkylating agent.
Step 4: Conclusion
Chlorambucil is the correctly identified alkylating agent.
Final Answer: (B)
Alkylating agents are a class of chemotherapy drugs that work by adding an alkyl group to DNA.
Step 2: Meaning
This chemical modification causes DNA cross-linking, which prevents the cell from replicating and eventually leads to cell death.
Step 3: Analysis
Methotrexate is an antimetabolite. Vincristine is a vinca alkaloid (microtubule inhibitor). Dactinomycin is an antitumor antibiotic. Chlorambucil is a nitrogen mustard derivative and a classic alkylating agent.
Step 4: Conclusion
Chlorambucil is the correctly identified alkylating agent.
Final Answer: (B)
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