Question:

Which one of the following intermediate metabolites is common for aerobic break down of glucose, aminoacid and fatty acids?

Show Hint

All three food types feed into the Krebs cycle through the same two-carbon compound.
Updated On: Nov 12, 2026
  • Glucose-6-phosphate
  • Fructose 1, 6 diphosphate
  • Pyruvic acid
  • Acetyl Co.A
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The Correct Option is D

Solution and Explanation

Step 1: Understanding the Concept
Carbohydrates, fats and proteins are all oxidised aerobically through the Krebs cycle.

Step 2: Glucose and fatty acids
Glucose is broken down by glycolysis to pyruvic acid, which forms acetyl CoA in mitochondria. Fatty acids undergo beta-oxidation, which removes two carbon units directly as acetyl CoA.

Step 3: Amino acids
After deamination, many amino acids give carbon skeletons that are converted to acetyl CoA.

Step 4: Why the other options fail
Glucose-6-phosphate and fructose-1,6-bisphosphate belong to sugar metabolism, and pyruvate is not formed in fatty acid oxidation.

Final Answer:
Acetyl CoA is the common intermediate. \[ \boxed{\text{(D) }\text{Acetyl Co.A}} \]
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