Question:

Which one of the following are Professional Antigen Presenting Cells?

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Professional APCs = Dendritic cells, Macrophages, B-cells.
Updated On: May 14, 2026
  • Fibroblasts
  • Neutrophils
  • Dendritic cells
  • Epithelial cells
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The Correct Option is C

Solution and Explanation


Step 1: Concept

Professional Antigen Presenting Cells (APCs) are specialized cells that express MHC-II and provide co-stimulatory signals to activate naive T-cells.

Step 2: Meaning

The three main professional APCs are Dendritic cells, Macrophages, and B-cells.

Step 3: Analysis

Dendritic cells are considered the most potent professional APCs because they are the only ones capable of activating naive T-cells and initiating a primary immune response. Fibroblasts and epithelial cells are non-professional APCs.

Step 4: Conclusion

Dendritic cells are the definitive professional APCs in the options provided. Final Answer: (C)
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