Question:
Which of the following set of compounds constitutes vasodilators?
Which of the following set of compounds constitutes vasodilators?
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Histamine + Bradykinin = key vasodilators in inflammation.
Updated On: Jul 18, 2026
- Heparin and histamine
- Heparin and serotonin
- Serotonin and bradykinin
- Histamine and bradykinin
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The Correct Option is D
Solution and Explanation
Step 1: Understanding vasodilation.
Vasodilation refers to widening of blood vessels due to relaxation of smooth muscles in vessel walls. It increases blood flow and reduces blood pressure locally.
Step 2: Role of histamine.
Histamine is released during allergic reactions and inflammation. It causes relaxation of smooth muscles in blood vessels leading to increased vascular permeability and vasodilation.
Step 3: Role of bradykinin.
Bradykinin is a peptide that induces strong vasodilation. It also increases pain sensation and promotes inflammatory responses in tissues.
Step 4: Evaluation of serotonin.
Serotonin generally causes vasoconstriction in most blood vessels, not vasodilation. Therefore, it does not belong to vasodilator group in this context.
Step 5: Evaluation of heparin.
Heparin is an anticoagulant and does not primarily function as a vasodilator. Its role is preventing blood clotting rather than altering vessel diameter.
Step 6: Final conclusion.
Thus, histamine and bradykinin together constitute vasodilators.
Vasodilation refers to widening of blood vessels due to relaxation of smooth muscles in vessel walls. It increases blood flow and reduces blood pressure locally.
Step 2: Role of histamine.
Histamine is released during allergic reactions and inflammation. It causes relaxation of smooth muscles in blood vessels leading to increased vascular permeability and vasodilation.
Step 3: Role of bradykinin.
Bradykinin is a peptide that induces strong vasodilation. It also increases pain sensation and promotes inflammatory responses in tissues.
Step 4: Evaluation of serotonin.
Serotonin generally causes vasoconstriction in most blood vessels, not vasodilation. Therefore, it does not belong to vasodilator group in this context.
Step 5: Evaluation of heparin.
Heparin is an anticoagulant and does not primarily function as a vasodilator. Its role is preventing blood clotting rather than altering vessel diameter.
Step 6: Final conclusion.
Thus, histamine and bradykinin together constitute vasodilators.
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