Which of the following phagocytic cells is NOT a tissue-specific macrophage cell?
Show Hint
- Histiocyte
- Kupffer cell
- Langerhans cell
- Dendritic cell
The Correct Option is D
Solution and Explanation
Step 1: Concept
Macrophages are resident phagocytes that take on specific names based on the tissue they occupy.
Step 2: Meaning
Dendritic cells, while related and phagocytic, are a distinct lineage of professional antigen-presenting cells.
Step 3: Analysis
Histiocytes are macrophages in connective tissue. Kupffer cells are macrophages in the liver. Langerhans cells are specific macrophages/dendritic-like cells in the skin. While "Dendritic cell" is a general category of cell found in many tissues, it is defined by its function in T-cell activation rather than being a "tissue-specific macrophage" subtype.
Step 4: Conclusion
The dendritic cell is classified separately from the resident macrophage system. Final Answer: (D)
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