Question:
Which of the following is true for bone tissue cell differentiation and maturation?
Which of the following is true for bone tissue cell differentiation and maturation?
Updated On: Feb 16, 2026
- Osteogenic→Osteblasts→Osteocytes
- Osteogenic→Osteblasts→Osteoclasts
- Osteocytes →Osteogenic→Osteblasts
- Ostoclasts→Osteblasts→Osteocytes
Show Solution
Verified By Collegedunia
The Correct Option is C
Solution and Explanation
The question provided revolves around the process of cell differentiation and maturation within bone tissue. The context is important as it pertains to the development of bone cells and their functional roles.
To address this question, let's analyze each given option and identify the correct sequence of differentiation and maturation of bone cells:
- Osteogenic → Osteoblasts → Osteocytes: This is the correct order of differentiation for bone cell development. Here's why:
- Osteogenic\ cells: These are the precursor or stem cells in the bone that have the potential to develop into osteoblasts. They are undifferentiated and play a crucial role in the bone regeneration process.
- Osteoblasts: These cells arise from osteogenic cells and are responsible for the synthesis of bone matrix and mineralization. They are actively involved in forming new bone tissue.
- Osteocytes: Once osteoblasts become embedded in the bone matrix they secrete, they mature into osteocytes. Osteocytes are mature bone cells that maintain the bone matrix.
- Osteogenic → Osteoblasts → Osteoclasts: This option is incorrect because osteoclasts do not derive from osteogenic cells. Osteoclasts are derived from the monocyte/macrophage lineage and are responsible for bone resorption.
- Osteocytes → Osteogenic → Osteoblasts: This sequence is incorrect as osteocytes cannot revert back to osteogenic cells, making this an illogical sequence in the differentiation process.
- Osteoclasts → Osteoblasts → Osteocytes: This is incorrect. Osteoclasts are involved in bone resorption and come from a different lineage than osteoblasts and osteocytes.
Conclusively, the logical and factual sequence of bone cell differentiation and maturation is: Osteogenic → Osteoblasts → Osteocytes.
Was this answer helpful?
0
0
Top GPAT Biopharmaceutics and Pharmacokinetics Questions
Decrease in effective surface area available to the dissolution medium leading to a fall in the dissolution rate, may happen due to which one of the following reasons?
- Match List I with List II
List I List II A When two dosage forms have equal t max I When their total body clearance is constant. B AUC values of the two analogs can be compared to measure relative bioavailability II Absorption rate constants are equal C Urinary data is valid to measure bioavailability. III. W III When fraction absorbed and elimination rate is constant. D C max is proportional to the rate of absorption IV Excretion of drug and/or metabolite is related to the bioavailable dose. Choose the correct answer from the options given below:
- For solid oral drug products, a change in the concentration of which of the following excipients is more likely to influence the bioavailability of a drug.
- For depot injections, in which drug is slowly released over weeks or months, which bioequivalence study design is used?
- Name the popular system for ocular delivery of pilocarpine, based on membrance -controlled reservoir systems
View More Questions
Top GPAT Bio-pharmaceutics Questions
- Method of Study Drug Distribution pattern is:
- Passive diffusion follows which order of kinetics
- Conc v/s time curve drown from single oral dose, which parameter can be calculated
- If a basic drug reabsorbed significantly from kidney which of the following statement will be correct
- The loading dose (DL) of a drug is usually based on the:
View More Questions
Top GPAT Questions
- Match the symbols in the List I with the terms used in the List II of conductance measurements, and
List I
SymbolsList II
TermsA \(\Omega^{-1}\) I Specific conductance B \(∧\) II Electrical conductance C k III Specific resistance D \(\rho\) IV Equivalent conductance
Choose the correct answer from the options given below: - Cottrell’s method is used for the measurement of:
- Match the statements in List I with their correct answers in List II, respectively, in respect to modified 1st law of thermodynamics, and
List I
List II
A Constant heat (q = 0) I Isothermal B Reversible process at constant temperature (dT = 0) II Isometric C Constant volume (dV = 0) III Adiabatic D Constant pressure (dP = 0) IV Isobar
Choose the correct answer from the options given below: - Boric acid with molecular weight 61.83 was partitioned between water and amyl alcohol at 25 °C. The amount of boric acid was determined to be 0.24 g in 250 ml of amyl alcohol and 0.32 g in 100 ml water. The partition coefficient of boric acid between water and amyl alcohol, when calculated at molar concentration for each of the solution, is:
- Drugs ‘A’, ‘B’ and ‘C’ follow zero order, first order and second order degradation kinetics, respectively, but have the same rate constant. Which of the following statement is true in this respect:
View More Questions