List of top Biopharmaceutics and Pharmacokinetics Questions on Bio-pharmaceutics

Formula of Renal clearance

In a two-compartment pharmacokinetic model, the central compartment represents which organ:

The clinical trial phase I, 60% of patients respond to Drug A, 50% of patients respond to Drug B, and 20% of patients respond to both Drug A and Drug B. how many randomly patients can response the drug

Which of the following is an example of physical incompatibility:

Histogram can be drawn only for:

In pharmacokinetic models, the term “compartment” means:

A hypertensive patient receiving a drug ‘Y’for managing BP was prescribed a tricyclic antidepressant. As a result, there was an abolition of the antihypertensive action of‘Y’. Which of the following drug could be ‘Y’?

A 70 kg woman was administered 1000 mg of the drug as i.v. bolus. After its uniform distribution in the body, the plasma concentration of the drug was found to be 50 mg/L. What is its volume of distribution?

Which of the following levels of IVIVC is represented by “the relatinship between one dissolution time point(e.g., t 50%) and one mean pharmacokinetic parameter, such as AUC, T_max or C_max”?

Which of the following is true for bone tissue cell differentiation and maturation?

Method of Study Drug Distribution pattern is:

For drug substances with highly variable pharmacokinetic characteristics the following Bioequivalence study design is used

When Ke is constant and Ka is larger:-

IVIVC utilizes the principles of statistical moment analysis:-

(Weight in pounds/150)* Adult Dose = Child dose. The above formula is known as________in Posology

In relation to buccal and sublingual route of administration which of the following statement is incorrect

Apparent volume of distribution will be highest in case of the drug with % plasmaprotein binding

Diazepam is not suitable for peroral sustained release form since

Method of inspections used to determine the absorption rate constants. It assumes that
(P) Ka is at least five time grater activities
(Q) Absorption in complete (i.e. > 95% complete) at the time of peak concentration
(R) Both Absorption and elimination are first order processes

What does 'pharmacokinetical compartment' mean

Bioavailability differences among drug's oral formulations are most likely to occur if it

Characteristics feature if hemorrhagic dengue fever is

Which of the following are the correct properties of ferroin? Ferroin is(P) 1, 10-phnathroline
(Q) A bidentate ligand complex
(R) Red in reduced form
(S) Blue in oxidized form