Question:
Which of the following is NOT a hepatotoxic drug?
Which of the following is NOT a hepatotoxic drug?
Show Hint
One of these is an oto and nephrotoxic aminoglycoside, not a liver toxin.
Updated On: Jun 24, 2026
- Chlorpropamide
- Allopurinol
- Streptomycin
- Halothane
Show Solution
Verified By Collegedunia
The Correct Option is C
Solution and Explanation
Step 1: This negative stem asks for the agent that does not damage the liver. The other three are classic causes of drug induced liver injury.
Step 2: Chlorpropamide is a first generation sulfonylurea that can cause cholestatic jaundice. Allopurinol can produce a hypersensitivity syndrome with hepatitis. Halothane is the textbook cause of halothane hepatitis, ranging from mild transaminase rise to fulminant hepatic necrosis.
Step 3: Streptomycin is an aminoglycoside antibiotic. Its main toxicities are ototoxicity (vestibular and cochlear damage) and nephrotoxicity, not liver injury.
Step 4: Because streptomycin is characteristically oto and nephrotoxic rather than hepatotoxic, it is the correct answer to a not hepatotoxic question.
Step 2: Chlorpropamide is a first generation sulfonylurea that can cause cholestatic jaundice. Allopurinol can produce a hypersensitivity syndrome with hepatitis. Halothane is the textbook cause of halothane hepatitis, ranging from mild transaminase rise to fulminant hepatic necrosis.
Step 3: Streptomycin is an aminoglycoside antibiotic. Its main toxicities are ototoxicity (vestibular and cochlear damage) and nephrotoxicity, not liver injury.
Step 4: Because streptomycin is characteristically oto and nephrotoxic rather than hepatotoxic, it is the correct answer to a not hepatotoxic question.
Was this answer helpful?
0
0
Top NEET PG Pharmacology Questions
- A bronchial asthma patient on inhalational steroids presented with white patchy lesions on the tongue and buccal mucosa. What is the drug that can be used to treat this condition?
- A pregnant woman with a history of bronchial asthma is in the third stage of labor. Which drugs should be avoided in managing postpartum hemorrhage in this mother?
- Name the drug that acts on both the marked areas.
- A patient with a previous history of myocardial infarction and ventricular arrhythmia is ontreatment for a few months. He developed fatigue, dyspnea, and weight gain. He had also developed pulmonary fibrosis. Which of the following drugs is responsible for the side effects mentioned above?
- A young female comes to the emergency department after consuming 100 aspirin tablets.What should be the next step in management?
View More Questions
Top NEET PG Drug-induced hyperuricemia / gout Questions
Top NEET PG Questions
- A patient hailing from Delhi presents with fever, arthralgia, and extensive petechial rash for 3 days. Lab investigations revealed a hemoglobin of 9 g/ dL, a white blood cell count of 9000 cells/mm3, a platelet count of 20000 cells/mm3, and a prolonged bleeding time. The clotting time was normal. What is the most likely diagnosis?
- Which of the following statements is true about Trichomonas vaginalis?
- A lady from West Rajasthan presented with an ulcer surrounded by erythema on the right leg. Microscopy of the biopsy from the edge of the ulcer showed organisms with dark staining nuclei and kinetoplast. What is the most likely causative agent?
- A child presents with a fever and a rash. Urine examination showed cells with owl's eye appearance. What is the most likely diagnosis?
- Infection with Clonorchis sinensis is associated with an increased risk of__?
View More Questions