Question:
Which of the following hormones secreted by kidney during deficiency of oxygen stimulates the bone marrow to produce more RBC?
Which of the following hormones secreted by kidney during deficiency of oxygen stimulates the bone marrow to produce more RBC?
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Erythropoietin from kidney regulates RBC production in response to low oxygen; key in hypoxia adaptation and clinical anemia treatments.
Updated On: Jun 19, 2026
- Renin
- Carbonic anhydrase
- Erythropoietin
- Adrenaline
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The Correct Option is C
Solution and Explanation
Step 1: Understanding oxygen deficiency.
- Oxygen deficiency (hypoxia) in tissues triggers a response to increase oxygen-carrying capacity of blood.
Step 2: Role of kidney.
- Specialized cells in kidney sense reduced oxygen levels.
- They secrete Erythropoietin hormone into blood.
Step 3: Action on bone marrow.
- Erythropoietin stimulates red bone marrow to increase the production of red blood cells (RBCs).
- This increases oxygen-carrying capacity of blood.
Step 4: Comparison with other options.
- Renin: regulates blood pressure via angiotensin pathway.
- Carbonic anhydrase: enzyme regulating pH and CO\(_2\) transport.
- Adrenaline: stress hormone, does not stimulate RBC production.
Step 5: Physiological significance.
- This feedback mechanism ensures tissues receive sufficient oxygen during hypoxia or blood loss.
Step 6: Conclusion.
Hence, the hormone responsible for stimulating RBC production during oxygen deficiency is Erythropoietin.
- Oxygen deficiency (hypoxia) in tissues triggers a response to increase oxygen-carrying capacity of blood.
Step 2: Role of kidney.
- Specialized cells in kidney sense reduced oxygen levels.
- They secrete Erythropoietin hormone into blood.
Step 3: Action on bone marrow.
- Erythropoietin stimulates red bone marrow to increase the production of red blood cells (RBCs).
- This increases oxygen-carrying capacity of blood.
Step 4: Comparison with other options.
- Renin: regulates blood pressure via angiotensin pathway.
- Carbonic anhydrase: enzyme regulating pH and CO\(_2\) transport.
- Adrenaline: stress hormone, does not stimulate RBC production.
Step 5: Physiological significance.
- This feedback mechanism ensures tissues receive sufficient oxygen during hypoxia or blood loss.
Step 6: Conclusion.
Hence, the hormone responsible for stimulating RBC production during oxygen deficiency is Erythropoietin.
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