Question:

Erythropoietin is produced by

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Remember: Erythropoietin is the key hormone regulating red blood cell production, mainly secreted by the kidney.
Updated On: Jun 19, 2026
  • Liver
  • Pancreas
  • Kidney
  • Spleen
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The Correct Option is C

Solution and Explanation

Step 1: Understanding Erythropoietin.
Erythropoietin (EPO) is a glycoprotein hormone responsible for stimulating red blood cell production in bone marrow.

Step 2: Site of production.

It is primarily secreted by specialized cells in the kidney (interstitial fibroblasts) in response to hypoxia.

Step 3: Mechanism.

Low oxygen levels in the blood trigger the kidneys to release EPO, which promotes the differentiation of hematopoietic stem cells into erythrocytes.

Step 4: Other organs.

While the liver produces small amounts of EPO during fetal development, the kidney is the main source in adults.

Step 5: Conclusion.

Thus, the correct answer is the kidney.
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