Question

Which of the following disorders follows autosomal recessive inheritance pattern?

• A. Huntington’s diseas
• B. Treacher collins syndrome
• C. Cystic fibrosis
• D. Achondroplasia

Answer 1

The Correct Option is C

In order to determine which disorder follows an autosomal recessive inheritance pattern, we should understand the nature of each condition:

• Huntington’s disease: This is a neurodegenerative genetic disorder that follows an autosomal dominant inheritance pattern, meaning only one copy of the mutated gene (from either parent) is sufficient to cause the disorder.
• Treacher Collins syndrome: This is a genetic condition affecting the development of bones and tissues of the face. It typically follows an autosomal dominant pattern but can also occur due to autosomal recessive inheritance in some cases.
• Cystic fibrosis: This is an autosomal recessive disorder, which means that both copies of the gene in each cell have mutations. The parents of the individual with an autosomal recessive condition each carry one copy of the mutated gene, but they usually do not show signs and symptoms of the condition.
• Achondroplasia: This condition is the most common form of dwarfism and follows an autosomal dominant inheritance pattern.

By understanding these patterns, we identify that Cystic fibrosis is inherited in an autosomal recessive manner.