Question:
Chloride level in sweat is used in the diagnosis of which disease?
Chloride level in sweat is used in the diagnosis of which disease?
Updated On: Jun 18, 2025
- Phenylketonuria
Cystic fibrosis
Gaucher's disease
Osteogenesis imperfecta
Show Solution
Verified By Collegedunia
The Correct Option is B
Solution and Explanation
The chloride level in sweat is a diagnostic indicator for cystic fibrosis. This condition is a genetic disorder that affects the respiratory and digestive systems. By performing a sweat test, which measures the concentration of chloride excreted in sweat, healthcare professionals can diagnose cystic fibrosis. An elevated chloride level typically indicates a positive result for the disease.
Explanation:
- Phenylketonuria: A metabolic disorder unrelated to sweat chloride levels; diagnosed through blood tests detecting phenylalanine levels.
- Cystic fibrosis: The sweat test reveals high chloride content, indicative of CFTR protein defects causing imbalance, leading to cystic fibrosis.
- Gaucher's disease: A lysosomal storage disorder diagnosed by enzyme activity measurements or genetic testing, not sweat tests.
- Osteogenesis imperfecta: Characterized by bone fragility, diagnosed based on clinical evaluation and genetic testing, not sweat chloride levels.
Was this answer helpful?
0
0
Top NEET PG Pediatrics Questions
- A newborn presented with chest retractions, dyspnea, and lethargy. The pediatrician diagnosed the baby with respiratory distress syndrome. This occurs due to the deficiency of:
- A 10-year-old child weighing 30 kg presents with a history of loose stools for 2 days. On examination, there is severe dehydration. Laboratory investigations are as follows. What is the initial management as per ISPAD guidelines?
RBS 550mg/dL pH 7.01 Na+ 158mEq/L Urine glucose 3+
- Which of the following is the best sign to indicate adequate growth in an infant with a birth weight of 2.8 kg?
- A 3-month-old baby complains of deafness, cataract, and patent ductus arteriosus. Which of the following is the most likely diagnosis?
- A child presents with fever and a rash spreading from the face, behind cheeks, and buccal mucosa to other body parts. On examination, Koplik's spot is present. What is the likely diagnosis?
View More Questions
Top NEET PG Pediatric Disorders Questions
- A newborn presented with chest retractions, dyspnea, and lethargy. The pediatrician diagnosed the baby with respiratory distress syndrome. This occurs due to the deficiency of:
- A child is brought to the hospital with respiratory distress and biphasic stridor. The radiograph is shown below. What is the diagnosis?
- A 3-month-old baby presents with jaundice and clay-coloured stools. Lab investigation reveals that the baby has conjugated hyperbilirubinemia. The liver biopsy shows periductal proliferation. What is the most likely diagnosis?
Top NEET PG Questions
- A patient hailing from Delhi presents with fever, arthralgia, and extensive petechial rash for 3 days. Lab investigations revealed a hemoglobin of 9 g/ dL, a white blood cell count of 9000 cells/mm3, a platelet count of 20000 cells/mm3, and a prolonged bleeding time. The clotting time was normal. What is the most likely diagnosis?
- Which of the following statements is true about Trichomonas vaginalis?
- A lady from West Rajasthan presented with an ulcer surrounded by erythema on the right leg. Microscopy of the biopsy from the edge of the ulcer showed organisms with dark staining nuclei and kinetoplast. What is the most likely causative agent?
- A child presents with a fever and a rash. Urine examination showed cells with owl's eye appearance. What is the most likely diagnosis?
- Infection with Clonorchis sinensis is associated with an increased risk of__?
View More Questions