Question:
Which enzyme is responsible for phosphorylation of glucose with ATP?
Which enzyme is responsible for phosphorylation of glucose with ATP?
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The first step of glycolysis transfers a phosphate group from ATP to glucose to form glucose-6-phosphate.
Updated On: Nov 12, 2026
- Hexokinase
- Phosphofructokinase
- Aldolase
- Phosphohexose isomerase
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The Correct Option is A
Solution and Explanation
Step 1: Understanding the Concept
In the first step of glycolysis, glucose is phosphorylated by ATP and becomes glucose-6-phosphate. A kinase enzyme carries out this transfer.
Step 2: Match each enzyme
Hexokinase phosphorylates glucose.
Phosphofructokinase phosphorylates fructose-6-phosphate.
Aldolase splits fructose-1,6-bisphosphate.
Phosphohexose isomerase converts glucose-6-phosphate into fructose-6-phosphate.
Step 3: Conclusion
Only hexokinase acts on glucose with ATP.
Final Answer:
The enzyme is hexokinase. \[ \boxed{\text{(A) }\text{Hexokinase}} \]
In the first step of glycolysis, glucose is phosphorylated by ATP and becomes glucose-6-phosphate. A kinase enzyme carries out this transfer.
Step 2: Match each enzyme
Hexokinase phosphorylates glucose.
Phosphofructokinase phosphorylates fructose-6-phosphate.
Aldolase splits fructose-1,6-bisphosphate.
Phosphohexose isomerase converts glucose-6-phosphate into fructose-6-phosphate.
Step 3: Conclusion
Only hexokinase acts on glucose with ATP.
Final Answer:
The enzyme is hexokinase. \[ \boxed{\text{(A) }\text{Hexokinase}} \]
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