Concept:
Intrauterine devices (IUDs) are contraceptive methods that prevent fertilization through different mechanisms.
Step 1: Types of IUDs.
• Non-medicated IUDs → e.g., Lippes loop
• Copper-releasing IUDs → e.g., Multiload 375
• Hormone-releasing IUDs → e.g., LNG-20
Step 2: Mechanism of non-medicated IUDs.
Non-medicated IUDs (like Lippes loop):
• Increase phagocytosis of sperms by macrophages in uterine cavity
Step 3: Analyze options.
• (A) LNG-20 → Hormone releasing $\times$
• (B) Multiload 375 → Copper IUD $\times$
• (C) Lippes loop → Non-medicated IUD, increases macrophage activity \checkmark
• (D) Vaults → Barrier method $\times$
Step 4: Conclusion.
\[
\text{Lippes loop attracts macrophages for sperm phagocytosis}
\]