Question:

Which contraceptive device attracts macrophages in the uterine cavity for phagocytosis of sperms?

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IUD types: Lippes = macrophages, Copper = spermicidal ions, LNG = hormonal effect.
Updated On: May 4, 2026
  • LNG - 20
  • Multiload 375
  • Lippes loop
  • Vaults
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The Correct Option is C

Solution and Explanation

Concept:
Intrauterine devices (IUDs) are contraceptive methods that prevent fertilization through different mechanisms.

Step 1:
Types of IUDs.
• Non-medicated IUDs → e.g., Lippes loop
• Copper-releasing IUDs → e.g., Multiload 375
• Hormone-releasing IUDs → e.g., LNG-20

Step 2:
Mechanism of non-medicated IUDs. Non-medicated IUDs (like Lippes loop):
• Increase phagocytosis of sperms by macrophages in uterine cavity

Step 3:
Analyze options.
• (A) LNG-20 → Hormone releasing $\times$
• (B) Multiload 375 → Copper IUD $\times$
• (C) Lippes loop → Non-medicated IUD, increases macrophage activity \checkmark
• (D) Vaults → Barrier method $\times$

Step 4:
Conclusion. \[ \text{Lippes loop attracts macrophages for sperm phagocytosis} \]
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