Question:

Which among the following represents the process of transamination?

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Transamination transfers an amino group from an amino acid to a keto acid.
Updated On: Nov 12, 2026
  • \(\alpha\)-ketoglutaric acid + \(\text{NH}_{4}^{+}\) + \(\text{NADPH}_{2}\rightarrow\) Glutamic acid + \(\text{H}_{2}\text{O}\) + NADP
  • Glutamic acid + Oxaloacetic acid \(\rightarrow\) \(\alpha\)-ketoglutaric acid + Aspartic acid
  • Glutamic acid + \(\text{NH}_{4}^{+}\) + ATP \(\rightarrow\) Glutamine + ADP
  • Aspartic acid + \(\text{NH}_{4}^{+}\) + ATP \(\rightarrow\) Asparagine + ADP
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The Correct Option is B

Solution and Explanation

Step 1: Understanding the Concept
Transamination is the transfer of the amino group from one amino acid to a keto acid, catalysed by transaminases. A new amino acid and a new keto acid are formed.

Step 2: Identify the reaction
Glutamic acid passes its amino group to oxaloacetic acid. Glutamic acid becomes \(\alpha\)-ketoglutaric acid and oxaloacetic acid becomes aspartic acid.

Step 3: Other reactions
Ketoglutaric acid with ammonium and NADPH is reductive amination. The ATP-driven reactions forming glutamine and asparagine are amidation.

Final Answer:
Glutamic acid with oxaloacetic acid giving ketoglutaric acid and aspartic acid is transamination. \[ \boxed{\text{(B) }\text{Glutamic acid + Oxaloacetic acid} \rightarrow \alpha\text{-ketoglutaric acid + Aspartic acid}} \]
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