Question:

When two phosphatidyl glycerol moieties join with each other with the elimination of one glycerol molecule, the resulting phospholipid formed is:

Show Hint

Cardiolipin is also called diphosphatidylglycerol.
The name itself reveals its structure: two phosphatidyl groups sharing a single central glycerol molecule.
  • Cardiolipin
  • Cephalin
  • Ceramide
  • Ganglioside
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The Correct Option is A

Solution and Explanation

Step 1: Understanding the Concept:
Phospholipids are structural components of biological membranes. Many complex lipids are formed through condensation reactions between simpler phospholipid precursors.

Step 2: Detailed Explanation:

Cardiolipin (diphosphatidylglycerol) is a unique, double-phospholipid molecule primarily located in the inner mitochondrial membrane.
Its chemical structure consists of two phosphatidylglycerol (PG) moieties linked together by a central glycerol backbone.
During biosynthesis, the enzyme cardiolipin synthase catalyzes the condensation of two PG molecules, releasing one free glycerol molecule in the process.
This reaction joins the two phosphate-bearing diacylglycerol scaffolds through a single glycerol bridge.
This structure gives cardiolipin four fatty acid tails and two negative charges, which help it stabilize the protein complexes involved in mitochondrial oxidative phosphorylation.

Step 3: Final Answer:

The lipid formed is cardiolipin, corresponding to option (A).
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