Question:
When two live vaccines are not given at the same visit, the ideal minimum time gap between them is:
When two live vaccines are not given at the same visit, the ideal minimum time gap between them is:
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If not given the same day, space two live vaccines by at least a month.
Updated On: Jun 23, 2026
- 2 weeks
- 4 weeks
- 8 weeks
- 12 weeks
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The Correct Option is B
Solution and Explanation
Step 1: Two live vaccines can be given on the same day at different sites with no problem. The issue arises only when they are NOT given together. Step 2: If live parenteral or live intranasal vaccines (for example MMR, varicella, zoster, yellow fever, and intranasal LAIV) are not administered at the same visit, they should be separated by at least 4 weeks. Step 3: The reason is that the immune response to the first live vaccine (interferon and other mediators) can interfere with replication and take of the second live vaccine if given too soon. Step 4: A gap shorter than 4 weeks (2 weeks) is insufficient, and 8 or 12 weeks is longer than the recommended minimum, so the correct minimum interval is 4 weeks.
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