Question:
What is the site of action of antihistamine?
What is the site of action of antihistamine?
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Antihistamines primarily act on the stomach wall to block histamine receptors involved in gastric acid secretion.
Updated On: Feb 9, 2026
- Small intestine
- Stomach wall
- Liver
- Large intestine
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The Correct Option is B
Solution and Explanation
Step 1: Understanding antihistamine action.
Antihistamines work by blocking the action of histamine, a substance involved in allergic reactions. The primary site of action for antihistamines is the stomach wall, where histamine receptors play a key role in gastric acid secretion.
Step 2: Analyzing the options.
(A) Small intestine: Incorrect. Antihistamines do not primarily act on the small intestine.
(B) Stomach wall: Correct. Antihistamines are commonly used to treat conditions like acid reflux by blocking histamine receptors in the stomach.
(C) Liver: Incorrect. The liver is involved in drug metabolism but is not the primary site of action for antihistamines.
(D) Large intestine: Incorrect. Antihistamines do not act specifically on the large intestine.
Step 3: Conclusion.
The correct answer is (B) Stomach wall, where antihistamines block histamine receptors to reduce gastric acid secretion.
Antihistamines work by blocking the action of histamine, a substance involved in allergic reactions. The primary site of action for antihistamines is the stomach wall, where histamine receptors play a key role in gastric acid secretion.
Step 2: Analyzing the options.
(A) Small intestine: Incorrect. Antihistamines do not primarily act on the small intestine.
(B) Stomach wall: Correct. Antihistamines are commonly used to treat conditions like acid reflux by blocking histamine receptors in the stomach.
(C) Liver: Incorrect. The liver is involved in drug metabolism but is not the primary site of action for antihistamines.
(D) Large intestine: Incorrect. Antihistamines do not act specifically on the large intestine.
Step 3: Conclusion.
The correct answer is (B) Stomach wall, where antihistamines block histamine receptors to reduce gastric acid secretion.
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