Question:

Vaccination in the last century had resulted in 100% reduction in active cases across the globe for

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Smallpox = First and only human disease eradicated globally.
Updated On: May 13, 2026
  • small pox
  • hepatitis B
  • tetanus
  • tuberculosis
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The Correct Option is A

Solution and Explanation

Concept: Vaccination has helped control many diseases, but only one disease has been completely eradicated globally.

Step 1:
Understand eradication.
Eradication means:
• Zero cases worldwide
• No natural occurrence of disease

Step 2:
Analyze options.

• Smallpox → Completely eradicated (WHO, 1980)
• Hepatitis B → Still present
• Tetanus → Still occurs
• Tuberculosis → Still widespread

Step 3:
Final conclusion.
Thus, the disease with 100% reduction is: \[ Smallpox \]
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