Step 1: Recall the function of Natural Killer (NK) cells.
Natural Killer (NK) cells are components of innate immunity that destroy virus-infected and tumour cells.
They release the protein
\[
\boxed{\text{Perforin}}
\]
which forms pores in the target cell membrane, leading to cell death.
Step 2: Eliminate the remaining options.
\[
\begin{aligned}
\text{T-lymphocytes} &\rightarrow \text{Cell-mediated immunity}
\text{B-lymphocytes} &\rightarrow \text{Antibody production}
\text{Spleen} &\rightarrow \text{Lymphoid organ}
\end{aligned}
\]
Step 3: Choose the correct option.
Hence,
\[
\boxed{(C)}
\]
is the correct answer.