Question:
The polyether ionophorous antibiotic with potent anticoccidial action is
The polyether ionophorous antibiotic with potent anticoccidial action is
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Common ionophores used in veterinary medicine include Monensin, Lasalocid, Salinomycin, and Maduramicin.
Note that ionophores are highly toxic to equines (horses), causing fatal myocardial necrosis.
Note that ionophores are highly toxic to equines (horses), causing fatal myocardial necrosis.
Updated On: Jul 14, 2026
- Arprinocid
- Halofuginone
- Monensin sodium
- Robenidine
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The Correct Option is C
Solution and Explanation
Step 1: Understanding the Concept:
Anticoccidials are drugs used to treat or prevent coccidiosis in animals.
They are broadly classified into synthetic chemical coccidiostats and polyether ionophores (ionophorous antibiotics obtained via fermentation of Streptomyces species).
Detailed Explanation:
Let us analyze the chemical classification of each of the given options:
(C) Monensin sodium: Monensin is a polyether ionophorous antibiotic produced by the fermentation of Streptomyces cinnamonensis.
It functions by forming lipophilic complexes with monovalent cations (primarily $Na^+$ and $K^+$), facilitating their transport across the cell membranes of coccidian sporozoites and merozoites.
This disrupts the osmotic balance of the parasite, leading to an influx of water, swelling, and eventual osmotic lysis.
It is widely used as an anticoccidial in poultry and as a rumen modifier in cattle.
(A) Arprinocid is a synthetic chemical coccidiostat belonging to the purine derivative class.
(B) Halofuginone is a synthetic chemical coccidiostat belonging to the quinazolinone class.
(D) Robenidine is a synthetic chemical coccidiostat belonging to the guanidine class.
Step 2: Final Answer:
Monensin sodium is the only polyether ionophorous antibiotic among the options.
Anticoccidials are drugs used to treat or prevent coccidiosis in animals.
They are broadly classified into synthetic chemical coccidiostats and polyether ionophores (ionophorous antibiotics obtained via fermentation of Streptomyces species).
Detailed Explanation:
Let us analyze the chemical classification of each of the given options:
(C) Monensin sodium: Monensin is a polyether ionophorous antibiotic produced by the fermentation of Streptomyces cinnamonensis.
It functions by forming lipophilic complexes with monovalent cations (primarily $Na^+$ and $K^+$), facilitating their transport across the cell membranes of coccidian sporozoites and merozoites.
This disrupts the osmotic balance of the parasite, leading to an influx of water, swelling, and eventual osmotic lysis.
It is widely used as an anticoccidial in poultry and as a rumen modifier in cattle.
(A) Arprinocid is a synthetic chemical coccidiostat belonging to the purine derivative class.
(B) Halofuginone is a synthetic chemical coccidiostat belonging to the quinazolinone class.
(D) Robenidine is a synthetic chemical coccidiostat belonging to the guanidine class.
Step 2: Final Answer:
Monensin sodium is the only polyether ionophorous antibiotic among the options.
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