Step 1: Identify the vertex and focus.
Vertex is
\[
(4,-1)
\]
Focus is
\[
(4,-3)
\]
Since both points have the same \(x\)-coordinate, the axis of the parabola is vertical.
Step 2: Find the value of \(a\).
For a vertical parabola with vertex \((h,k)\), standard form is
\[
(x-h)^2=4a(y-k)
\]
Here,
\[
(h,k)=(4,-1)
\]
Focus is
\[
(h,k+a)
\]
So,
\[
(4,-1+a)=(4,-3)
\]
Therefore,
\[
-1+a=-3
\]
\[
a=-2
\]
Step 3: Write the equation of the parabola.
Using
\[
(x-h)^2=4a(y-k),
\]
we get
\[
(x-4)^2=4(-2)(y+1)
\]
\[
(x-4)^2=-8(y+1)
\]
Step 4: Convert into general form.
Expanding,
\[
x^2-8x+16=-8y-8
\]
Bring all terms to one side:
\[
x^2-8x+8y+24=0
\]
Step 5: Final conclusion.
Therefore, the required parabola is
\[
\boxed{x^2-8x+8y+24=0}
\]