Question:
The most common karyotype in true hermaphroditism is:
The most common karyotype in true hermaphroditism is:
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About 90 percent of true hermaphrodites are 46 XX with an ovotestis.
Updated On: Jun 24, 2026
- 45 X0 with streak gonads
- 46 XX with ovotestis
- 47 XY +9
- 47 XX
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The Correct Option is B
Solution and Explanation
Step 1: True hermaphroditism, now called ovotesticular disorder of sexual differentiation (ovotesticular DSD), is one of the rarest intersex anomalies and is defined by the presence of both ovarian and testicular tissue (an ovotestis) in the same individual.
Step 2: In about 90 percent of cases the karyotype is 46 XX. Therefore the most common karyotype is 46 XX, and these patients have ovotestes. This makes option 2 (46 XX with ovotestis) correct.
Step 3: Why the others are wrong. 45 X0 with streak gonads is Turner syndrome, not true hermaphroditism. 47 XY +9 is an unrelated trisomy and not a recognised ovotesticular karyotype. 47 XX is not a standard karyotype for this condition. Rarely 46 XY or 46 XX/46 XY mosaicism occurs, but the predominant karyotype is 46 XX.
Step 2: In about 90 percent of cases the karyotype is 46 XX. Therefore the most common karyotype is 46 XX, and these patients have ovotestes. This makes option 2 (46 XX with ovotestis) correct.
Step 3: Why the others are wrong. 45 X0 with streak gonads is Turner syndrome, not true hermaphroditism. 47 XY +9 is an unrelated trisomy and not a recognised ovotesticular karyotype. 47 XX is not a standard karyotype for this condition. Rarely 46 XY or 46 XX/46 XY mosaicism occurs, but the predominant karyotype is 46 XX.
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