Question:

The “Microglial Cells” found in human brain, represent which of the following class of innate immune cells?

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• Microglia = Brain macrophages
• CNS immune defense cells
Updated On: May 13, 2026
  • NK cells
  • Macrophages
  • Eosinophils
  • Neutrophils
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The Correct Option is B

Solution and Explanation

Concept: Microglial cells are the resident immune cells of the central nervous system (CNS).
• Derived from monocyte/macrophage lineage
• Function as phagocytic cells in the brain

Step 1:
Analyzing each option.

NK cells: Involved in killing infected or tumor cells → Not resident brain macrophages.
Macrophages: Phagocytic immune cells; microglia are specialized CNS macrophages → Correct.
Eosinophils: Involved in parasitic infections → Incorrect.
Neutrophils: First responders in inflammation, not resident CNS cells → Incorrect.

Step 2:
Selecting the correct answer.
Thus, microglial cells are macrophage-like cells.
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