Question

Optimum moisture content in capsule shell is ____%.

• A. 10-12
• B. 12-15
• C. 12-18
• D. 16-18

Hint:

Below 12% makes them brittle; above 15% makes them soggy. Stay in the 12-15% "sweet spot."

Answer 1

The Correct Option is B

Step 1: Concept
Hard gelatin capsule shells are manufactured using a mixture of gelatin, plasticizers, and water.

Step 2: Meaning
Moisture acts as a plasticizer for the gelatin; if the content is too low, capsules become brittle, and if too high, they become soft and prone to microbial growth.

Step 3: Analysis
Pharmaceutical standards require a specific range to maintain the structural integrity and stability of the shell. Experimental data and pharmacopoeial guidelines establish that a range of 12-15% is ideal.

Step 4: Conclusion
Therefore, 12-15% is the optimum moisture content for hard gelatin capsule shells.

Final Answer: (B)