Question:

Neurotransmitters can be either excitatory or inhibitory, depending on where they are released, what receptors they bind to, and the ionic conditions that they encounter. Which of the following is a group of excitatory neurotransmitters?

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- Glutamate = main excitatory - GABA & Glycine = inhibitory - Acetylcholine often excitatory
Updated On: May 13, 2026
  • Glycine and Glutamate
  • $\gamma$-aminobutyric acid (GABA) and Glycine
  • Glutamate, Acetylcholine and Serotonin
  • $\gamma$-aminobutyric acid (GABA) and Serotonin
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The Correct Option is C

Solution and Explanation

Concept: Neurotransmitters are classified based on their effect:
Excitatory → Increase likelihood of action potential
Inhibitory → Decrease likelihood of action potential

Step 1:
Identify inhibitory neurotransmitters.

• GABA → Major inhibitory neurotransmitter
• Glycine → Inhibitory neurotransmitter

Step 2:
Identify excitatory neurotransmitters.

• Glutamate → Major excitatory neurotransmitter
• Acetylcholine → Often excitatory
• Serotonin → Generally excitatory/modulatory

Step 3:
Analyze options.

• (A) Contains glycine → inhibitory → incorrect
• (B) Both inhibitory → incorrect
• (C) All excitatory → correct
• (D) Contains GABA → inhibitory → incorrect

Step 4:
Final conclusion.
Thus, the correct group is: \[ Glutamate, Acetylcholine and Serotonin \]
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