Question

Match the LIST-I with LIST-II:

• A. A-II, B-III, C-I, D-IV
• B. A-II, B-I, C-IV, D-III
• C. A-IV, B-II, C-I, D-III
• D. A-III, B-IV, C-II, D-I

Hint:

Memory check: Pasteur = Oxygen is good (saves glucose). Crabtree = Too much sugar is bad (forces fermentation). Both are critical for optimizing yield in industrial fermenters.

Answer 1

The Correct Option is B

Concept: This question links structural biochemistry (protein folding) with metabolic regulatory effects observed in microbial and cellular bioprocessing.

Step 1: Match A and B (Protein Structure).
Quaternary structure (A) refers to the level of protein organization where multiple polypeptide chains assemble (II) into a functional unit. Hydrophobic interactions (B) are the primary driving force for the folding of proteins in a wet environment (I), as non-polar side chains cluster together to avoid water.

Step 2: Match C (Crabtree Effect).
The Crabtree effect (C) occurs in certain yeast (like *S. cerevisiae*) where high glucose concentrations cause respiration inhibition (IV) even in the presence of oxygen, leading to ethanol production.

Step 3: Match D (Pasteur Effect).
The Pasteur effect (D) is the reverse metabolic observation where the presence of oxygen causes the suppression of glycolysis (III) (fermentation), as aerobic respiration is a more energy-efficient way to utilize glucose.