Question

Match List-I with List-II
List-I (Egg proteins):
(A) Ovomacroglobulin
(B) Ovomucoid
(C) Ovotransferrin
(D) Avidin
List-II (Functional properties):
(I) Binds biotin
(II) Strongly antigenic
(III) Binds metallic ions
(IV) Inhibits trypsin
Choose the correct answer from the options given below:

• (A) - (I), (B) - (III), (C) - (II), (D) - (IV)
• (A) - (II), (B) - (IV), (C) - (III), (D) - (I)
• (A) - (II), (B) - (III), (C) - (IV), (D) - (I)
• (A) - (I), (B) - (II), (C) - (IV), (D) - (III)

Hint:

Avidin's binding to biotin is one of the strongest known non-covalent biological interactions.
Eating raw egg whites can lead to a biotin deficiency because the active avidin prevents biotin absorption in the gut.

Answer 1

The Correct Option is B

Step 1: Understanding the Concept:
Egg white (albumen) contains a variety of functional proteins, many of which have biological activities that protect the developing embryo from microbial infection.
Detailed Explanation:
Let us analyze and match each egg protein with its primary functional property:
- (A) Ovomacroglobulin: This is a large glycoprotein that makes up about \(0.5\%\) of egg white protein. It is highly immunogenic and is recognized as being strongly antigenic (II).
- (B) Ovomucoid: This is a heat-resistant glycoprotein that constitutes about \(11\%\) of egg white. It is a well-known proteinase inhibitor that specifically inhibits trypsin (IV), preventing the enzymatic breakdown of egg proteins.
- (C) Ovotransferrin: Also known as conalbumin, this protein makes up about \(12\%\) of egg white. It is a metal-chelating glycoprotein that binds metallic ions (III), particularly \(Fe^{3+}\). By sequestering iron, it deprives bacteria of a vital nutrient, acting as an antimicrobial agent.
- (D) Avidin: This is a trace protein in egg white that forms an extremely strong non-covalent bond with biotin (I). This binding makes biotin unavailable to microorganisms, serving as an antimicrobial barrier.
Combining these individual matches:
\[ (A) \rightarrow (II), \quad (B) \rightarrow (IV), \quad (C) \rightarrow (III), \quad (D) \rightarrow (I) \] This matches option (B).

Step 2: Final Answer:
The correct match is (A) - (II), (B) - (IV), (C) - (III), (D) - (I).