Question

Match List-I with List-II 
 
Choose the correct answer from the options given below:} 
 

• (A) - (II), (B) - (III), (C) - (IV), (D) - (I)
• (A) - (II), (B) - (III), (C) - (I), (D) - (IV)
• (A) - (III), (B) - (I), (C) - (IV), (D) - (II)
• (A) - (III), (B) - (IV), (C) - (I), (D) - (II)

Hint:

To easily differentiate respiratory agents:
- Mucolytics (Bromhexine, Acetylcysteine): Actively break down mucus fibers to thin the secretions.
- Reflex Expectorants (Ipecac): Irritate the stomach to reflexively increase watery secretions.

Answer 1

The Correct Option is C

Step 1: Understanding the Concept:
Respiratory drugs include expectorants, which are used to increase the volume or decrease the viscosity of respiratory secretions, making it easier for the animal to clear them from the airway.

Step 2: Detailed Explanation:
Let us match each class of expectorant with its representative agent:
- (A) Reflex-acting secretory expectorant: This matches with Ipecacuanha (III).
Ipecacuanha contains alkaloids that irritate the gastric mucosa, reflexively stimulating bronchial secretions via vagal pathway excitation. Thus, (A) matches with (III).
- (B) Direct-acting secretory expectorant: This matches with Guaiphenesin (I).
Once absorbed, guaiphenesin is excreted directly into the respiratory tract, where it stimulates the bronchial secretory cells to produce thin, watery mucus. Thus, (B) matches with (I).
- (C) Diluent expectorant: This matches with Steam or water aerosols (IV).
Direct inhalation of steam or water aerosols hydrates and dilutes the mucus on the airway surface, facilitating clearance. Thus, (C) matches with (IV).
- (D) Mucolytic expectorant: This matches with Bromhexine (II).
Bromhexine is a mucolytic agent that breaks down the acid mucopolysaccharide fibers in sputum, directly reducing the viscosity of thick mucus. Thus, (D) matches with (II).
This matching sequence gives: (A) - (III), (B) - (I), (C) - (IV), (D) - (II).

Step 3: Final Answer:
The correct match is (A) - (III), (B) - (I), (C) - (IV), (D) - (II). This corresponds to option (C).