Question

Match List - I with List - II. 

Choose the correct answer from the options given below : 
 

• A. A-II, B-III, C-IV, D-I
• B. A-III, B-IV, C-I, D-II
• C. A-IV, B-I, C-II, D-III
• D. A-I, B-II, C-III, D-IV

Hint:

Vitamin Coenzyme memory anchors:
B1 (Thiamine) $\rightarrow$ TPP Cocarboxylase (Energy metabolism).
B2 (Riboflavin) $\rightarrow$ FAD/FMN (Flavin = Riboflavin).
B6 (Pyridoxine) $\rightarrow$ Pyridoxal Phosphate (PLP).
B9 (Folic Acid) $\rightarrow$ Tetrahydrofolate (THF).

Answer 1

The Correct Option is B

Step 1: Concept:
This question tests nutritional biochemistry, requiring you to correctly match essential B-complex vitamins with their biologically active coenzyme forms used in cellular metabolism.

Step 2: Step-by-step Explanation:

• A. Vitamin B$_1$ (Thiamine): Its active coenzyme form is Thiamine Pyrophosphate (TPP). TPP is historically and clinically also known as Cocarboxylase because it acts as an essential cofactor for decarboxylation reactions (like Pyruvate dehydrogenase). Thus, A matches with III.

• B. Vitamin B$_2$ (Riboflavin): Its active coenzyme forms are Flavin Mononucleotide (FMN) and Riboflavin adenine dinucleotide (FAD). These are crucial electron carriers in the Krebs cycle and Electron Transport Chain. Thus, B matches with IV.

• C. Vitamin B$_6$ (Pyridoxine): Its biologically active coenzyme form is Pyridoxal phosphate (PLP). PLP is vital for amino acid metabolism, particularly in transamination reactions. Thus, C matches with I.

• D. Folic acid (Vitamin B$_9$): Within the body, folic acid is reduced to its metabolically active form, Tetrahydrofolic acid (THF), which is essential for one-carbon metabolism and DNA synthesis. Thus, D matches with II.

• Compiling the correct pairs yields: A-III, B-IV, C-I, D-II.

Step 3: Final Answer:
Option (B) represents the correct sequence of matches.